Photodynamic Therapy (PDT) 

Photodynamic Therapy is based on the stimulation of a light-sensitive substance (photosensitizer) which is infused into the bloodstream, injected locally or applied in form of a cream. The photosensitizer binds with high specificity to pathologically changed tissue. When stimulated by (laser) light active oxygen radicals form and destroy this tissue without harming the surrounding healthy tissue.  

The most common photosensitizers are: 

  • Riboflavin
  • Hypericin
  • Chlorin E6
  • Indocyanine green (ICG)
  • Curcumin

They can be administered orally or as infusion. 

Besides photodynamic tumor therapy PDT can be performed to treat bacterial, viral and parasitic diseases (anti-microbial PDT). The key benefit of this approach is the combat of multiresistant pathogens. 

Areas of application

  • Tumors
  • Viruses (Hepatitis, HIV, Herpes etc.)
  • Bacterial infections
  • Chronic Lyme disease
  • Multiresistant Staphylococci
  • Parasitic diseases

Laser modules and photosensitizers

For more information, please navigate your mouse over the symbols.

 
  

Application

Principles of photodynamic cancer therapy 

Explaining the method of photodynamic cancer therapy in combination with liposomal indocyanine green as photosensitizer and infrared laser light, ultrasound and shockwaves as stimulants.  

 

Interstitial photodynamic breast tumor treatment with the Weberneedle® Endo Laser

Clinical application of interstitial infrared laser therapy (100 mW, 810 nm) after administration of liposomal indocyanine green as photosensitizer.  

 

External photodynamic treatment of a squamous cell carcinoma of the tongue and lymph node metastases with the Weberneedle® Compact Laser  

Clinical application of external infrared laser therapy (100 mW, 810 nm) after administration of liposomal indocyanine green as photosensitizer using the laser shower.

Accessories

  • Weberneedle® Lasercath

  • Weberneedle® Plastic Cannula 22 G

  • Weberneedle® Butterfly 21 G

  • Weberneedle® IV Catheter (Y-type) 20 G

  • Weberneedle® Lasercath with puncture needle 21 G